LATAM Airlines flight LA 6381: Multiple routes

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Select flight date:
FLIGHT SCHEDULE
Direct Codeshare Flights:
Sun 06:30 Charleston (CHS) 07:46 Atlanta (ATL) S
LA 6381 Non-stop Boeing 737-900 (739) 1:16 Effective 2025-10-26 through 2025-11-02
Codeshare flight, operated by Delta Air Lines.(DL 2124)
Daily 06:30 Charleston (CHS) 07:50 Atlanta (ATL) S
LA 6381 Non-stop Boeing 737-900 (739) 1:20 Effective 2026-01-06 through 2026-01-26
Codeshare flight, operated by Delta Air Lines.(DL 2124)
Daily 06:30 Charleston (CHS) 07:50 Atlanta (ATL) S
LA 6381 Non-stop Boeing 737-900 (739) 1:20 Effective from 2026-02-10
Codeshare flight, operated by Delta Air Lines.(DL 2124)
Tue 08:00 New York John F. Kennedy (JFK) 4 10:17 Cincinnati (CVG)
LA 6381 Non-stop Canadair CRJ 900 (CR9) 2:17 Operates only on 2025-10-28
Codeshare flight, operated by Delta Air Lines.(DL 4985)
Sun 09:30 Los Angeles (LAX) 3 14:23 San Antonio (SAT) A
LA 6381 Non-stop Airbus A319 (319) 2:53 Operates only on 2025-07-06
Codeshare flight, operated by Delta Air Lines.(DL 1024)
Tue 10:35 Chicago O'Hare (ORD) 5 13:59 New York John F. Kennedy (JFK) 4
LA 6381 Non-stop Canadair CRJ 900 (CR9) 2:24 Effective 2025-06-10 through 2025-06-24
Codeshare flight, operated by Delta Air Lines.(DL 5227)
Thu 13:45 Chicago O'Hare (ORD) 5 16:53 Atlanta (ATL) S
LA 6381 Non-stop Boeing 737-900 (739) 2:08 Operates only on 2025-07-03
Codeshare flight, operated by Delta Air Lines.(DL 1456)
Wed 13:55 Pittsburgh (PIT) 15:41 Atlanta (ATL) S
LA 6381 Non-stop Boeing 737-900 (739) 1:46 Effective 2025-06-11 through 2025-06-25
Codeshare flight, operated by Delta Air Lines.(DL 882)
Daily 16:15 Charlotte (CLT) 18:30 New York John F. Kennedy (JFK) 4
LA 6381 Non-stop Canadair CRJ 900 (CR9) 2:15 Effective 2025-09-08 through 2025-10-24
Codeshare flight, operated by Delta Air Lines.(DL 5053)
Daily 16:15 Charlotte (CLT) 18:30 New York John F. Kennedy (JFK) 4
LA 6381 Non-stop Canadair CRJ 900 (CR9) 2:15 Effective 2025-11-03 through 2025-12-23
Codeshare flight, operated by Delta Air Lines.(DL 5053)
Mon,Sun 16:15 Charlotte (CLT) 18:30 New York John F. Kennedy (JFK) 4
LA 6381 Non-stop Canadair CRJ 900 (CR9) 2:15 Effective 2026-01-04 through 2026-01-05
Codeshare flight, operated by Delta Air Lines.(DL 5053)
Wed 16:20 Dallas Fort Worth (DFW) E 17:45 Los Angeles (LAX) 3
LA 6381 Non-stop Airbus A319 (319) 3:25 Operates only on 2025-10-29
Codeshare flight, operated by Delta Air Lines.(DL 948)
Fri 16:26 Midway, Chicago (MDW) 19:35 Atlanta (ATL) S
LA 6381 Non-stop Boeing 717 (717) 2:09 Operates only on 2025-07-04
Codeshare flight, operated by Delta Air Lines.(DL 1739)
Daily 16:33 Charlotte (CLT) 18:48 New York John F. Kennedy (JFK) 4
LA 6381 Non-stop Canadair CRJ 900 (CR9) 2:15 Effective 2025-12-24 through 2026-01-03
Codeshare flight, operated by Delta Air Lines.(DL 5053)
Daily 16:49 Atlanta (ATL) S 17:57 Houston Hobby (HOU)
LA 6381 Non-stop Boeing 717 (717) 2:08 Effective 2025-05-07 through 2025-06-07
Codeshare flight, operated by Delta Air Lines.(DL 1254)
Mon,Thu,Fri,Sun 16:50 Atlanta (ATL) S 18:01 Jacksonville (JAX)
LA 6381 Non-stop Airbus A321 (321) 1:11 Effective 2025-06-08 through 2025-06-27
Codeshare flight, operated by Delta Air Lines.(DL 2627)
Daily 17:15 Boston Logan (BOS) A 18:55 New York John F. Kennedy (JFK) 4
LA 6381 Non-stop Embraer EMB 175 (E75) 1:40 Valid until 2025-05-06
Codeshare flight, operated by Delta Air Lines.(DL 5617)
Daily 17:25 Charlotte (CLT) 19:47 New York John F. Kennedy (JFK) 4
LA 6381 Non-stop Canadair CRJ 900 (CR9) 2:22 Effective 2025-07-07 through 2025-09-07
Codeshare flight, operated by Delta Air Lines.(DL 5053)
Mon,Fri,Sat 19:30 Ronald Reagan Washington (DCA) 2 21:32 Atlanta (ATL) S
LA 6381 Non-stop Airbus A320 (320) 2:02 Effective 2025-10-25 through 2025-11-01
Codeshare flight, operated by Delta Air Lines.(DL 1007)
Thu 21:20 Santa Ana (SNA) 04:32 Atlanta (ATL) S
LA 6381 Non-stop Boeing 757-200 (75W) 4:12 Operates only on 2025-10-30
Codeshare flight, operated by Delta Air Lines.(DL 543)
The flight arrives 1 day after departure.
Sat 21:45 Atlanta (ATL) S 22:53 Jacksonville (JAX)
LA 6381 Non-stop Boeing 757 (757) 1:08 Effective 2025-06-14 through 2025-06-28
Codeshare flight, operated by Delta Air Lines.(DL 1001)
Mon-Wed,Sat,Sun 21:45 Atlanta (ATL) S 22:53 Jacksonville (JAX)
LA 6381 Non-stop Boeing 757 (757) 1:08 Effective 2025-06-29 through 2025-07-05
Codeshare flight, operated by Delta Air Lines.(DL 1001)
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This flight number is listed as serving the following routes:


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LATAM Airlines flight LA 6381: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Codeshare Flights:
LATAM Airlines LA6381
06:30
Charleston (CHS)

07:46
Atlanta (ATL) S
Effective 2025-10-26 through 2025-11-02
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Codeshare flight, operated by Delta Air Lines. (DL 2124)
Duration: 1:16, non-stop
Boeing 737-900 (739)
LATAM Airlines LA6381
06:30
Charleston (CHS)

07:50
Atlanta (ATL) S
Effective 2026-01-06 through 2026-01-26
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by Delta Air Lines. (DL 2124)
Duration: 1:20, non-stop
Boeing 737-900 (739)
LATAM Airlines LA6381
06:30
Charleston (CHS)

07:50
Atlanta (ATL) S
Effective from 2026-02-10
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by Delta Air Lines. (DL 2124)
Duration: 1:20, non-stop
Boeing 737-900 (739)
LATAM Airlines LA6381
08:00
New York John F. Kennedy (JFK) 4

10:17
Cincinnati (CVG)
Operates only on 2025-10-28
Mon
-
Tue
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Codeshare flight, operated by Delta Air Lines. (DL 4985)
Duration: 2:17, non-stop
Canadair CRJ 900 (CR9)
LATAM Airlines LA6381
09:30
Los Angeles (LAX) 3

14:23
San Antonio (SAT) A
Operates only on 2025-07-06
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Codeshare flight, operated by Delta Air Lines. (DL 1024)
Duration: 2:53, non-stop
Airbus A319 (319)
LATAM Airlines LA6381
10:35
Chicago O'Hare (ORD) 5

13:59
New York John F. Kennedy (JFK) 4
Effective 2025-06-10 through 2025-06-24
Mon
-
Tue
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Codeshare flight, operated by Delta Air Lines. (DL 5227)
Duration: 2:24, non-stop
Canadair CRJ 900 (CR9)
LATAM Airlines LA6381
13:45
Chicago O'Hare (ORD) 5

16:53
Atlanta (ATL) S
Operates only on 2025-07-03
Mon
-
Tue
-
Wed
-
Thu
Fri
-
Sat
-
Sun
-
Codeshare flight, operated by Delta Air Lines. (DL 1456)
Duration: 2:08, non-stop
Boeing 737-900 (739)
LATAM Airlines LA6381
13:55
Pittsburgh (PIT)

15:41
Atlanta (ATL) S
Effective 2025-06-11 through 2025-06-25
Mon
-
Tue
-
Wed
Thu
-
Fri
-
Sat
-
Sun
-
Codeshare flight, operated by Delta Air Lines. (DL 882)
Duration: 1:46, non-stop
Boeing 737-900 (739)
LATAM Airlines LA6381
16:15
Charlotte (CLT)

18:30
New York John F. Kennedy (JFK) 4
Effective 2025-09-08 through 2025-10-24
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by Delta Air Lines. (DL 5053)
Duration: 2:15, non-stop
Canadair CRJ 900 (CR9)
LATAM Airlines LA6381
16:15
Charlotte (CLT)

18:30
New York John F. Kennedy (JFK) 4
Effective 2025-11-03 through 2025-12-23
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by Delta Air Lines. (DL 5053)
Duration: 2:15, non-stop
Canadair CRJ 900 (CR9)
LATAM Airlines LA6381
16:15
Charlotte (CLT)

18:30
New York John F. Kennedy (JFK) 4
Effective 2026-01-04 through 2026-01-05
Mon
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Codeshare flight, operated by Delta Air Lines. (DL 5053)
Duration: 2:15, non-stop
Canadair CRJ 900 (CR9)
LATAM Airlines LA6381
16:20
Dallas Fort Worth (DFW) E

17:45
Los Angeles (LAX) 3
Operates only on 2025-10-29
Mon
-
Tue
-
Wed
Thu
-
Fri
-
Sat
-
Sun
-
Codeshare flight, operated by Delta Air Lines. (DL 948)
Duration: 3:25, non-stop
Airbus A319 (319)
LATAM Airlines LA6381
16:26
Midway, Chicago (MDW)

19:35
Atlanta (ATL) S
Operates only on 2025-07-04
Mon
-
Tue
-
Wed
-
Thu
-
Fri
Sat
-
Sun
-
Codeshare flight, operated by Delta Air Lines. (DL 1739)
Duration: 2:09, non-stop
Boeing 717 (717)
LATAM Airlines LA6381
16:33
Charlotte (CLT)

18:48
New York John F. Kennedy (JFK) 4
Effective 2025-12-24 through 2026-01-03
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by Delta Air Lines. (DL 5053)
Duration: 2:15, non-stop
Canadair CRJ 900 (CR9)
LATAM Airlines LA6381
16:49
Atlanta (ATL) S

17:57
Houston Hobby (HOU)
Effective 2025-05-07 through 2025-06-07
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by Delta Air Lines. (DL 1254)
Duration: 2:08, non-stop
Boeing 717 (717)
LATAM Airlines LA6381
16:50
Atlanta (ATL) S

18:01
Jacksonville (JAX)
Effective 2025-06-08 through 2025-06-27
Mon
Tue
-
Wed
-
Thu
Fri
Sat
-
Sun
Codeshare flight, operated by Delta Air Lines. (DL 2627)
Duration: 1:11, non-stop
Airbus A321 (321)
LATAM Airlines LA6381
17:15
Boston Logan (BOS) A

18:55
New York John F. Kennedy (JFK) 4
Valid until 2025-05-06
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by Delta Air Lines. (DL 5617)
Duration: 1:40, non-stop
Embraer EMB 175 (E75)
LATAM Airlines LA6381
17:25
Charlotte (CLT)

19:47
New York John F. Kennedy (JFK) 4
Effective 2025-07-07 through 2025-09-07
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by Delta Air Lines. (DL 5053)
Duration: 2:22, non-stop
Canadair CRJ 900 (CR9)
LATAM Airlines LA6381
19:30
Ronald Reagan Washington (DCA) 2

21:32
Atlanta (ATL) S
Effective 2025-10-25 through 2025-11-01
Mon
Tue
-
Wed
-
Thu
-
Fri
Sat
Sun
-
Codeshare flight, operated by Delta Air Lines. (DL 1007)
Duration: 2:02, non-stop
Airbus A320 (320)
LATAM Airlines LA6381
21:20
Santa Ana (SNA)

04:32(+1)
Atlanta (ATL) S
Operates only on 2025-10-30
Mon
-
Tue
-
Wed
-
Thu
Fri
-
Sat
-
Sun
-
Codeshare flight, operated by Delta Air Lines. (DL 543)
Duration: 4:12, non-stop
Boeing 757-200 (75W)
The flight arrives 1 day after departure.
LATAM Airlines LA6381
21:45
Atlanta (ATL) S

22:53
Jacksonville (JAX)
Effective 2025-06-14 through 2025-06-28
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Codeshare flight, operated by Delta Air Lines. (DL 1001)
Duration: 1:08, non-stop
Boeing 757 (757)
LATAM Airlines LA6381
21:45
Atlanta (ATL) S

22:53
Jacksonville (JAX)
Effective 2025-06-29 through 2025-07-05
Mon
Tue
Wed
Thu
-
Fri
-
Sat
Sun
Codeshare flight, operated by Delta Air Lines. (DL 1001)
Duration: 1:08, non-stop
Boeing 757 (757)
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This flight number is listed as serving the following routes:
  • Atlanta (ATL) - Houston Hobby (HOU)
  • Atlanta (ATL) - Jacksonville (JAX)
  • Boston Logan (BOS) - New York John F. Kennedy (JFK)
  • Charleston (CHS) - Atlanta (ATL)
  • Charlotte (CLT) - New York John F. Kennedy (JFK)
  • Chicago O'Hare (ORD) - Atlanta (ATL)
  • Chicago O'Hare (ORD) - New York John F. Kennedy (JFK)
  • Dallas Fort Worth (DFW) - Los Angeles (LAX)
  • Los Angeles (LAX) - San Antonio (SAT)
  • Midway, Chicago (MDW) - Atlanta (ATL)
  • New York John F. Kennedy (JFK) - Cincinnati (CVG)
  • Pittsburgh (PIT) - Atlanta (ATL)
  • Ronald Reagan Washington (DCA) - Atlanta (ATL)
  • Santa Ana (SNA) - Atlanta (ATL)
All LATAM Airlines flights
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