American Airlines flight AA 4780: Multiple routes

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FLIGHT SCHEDULE
Direct Flights:
Sat 05:46 Syracuse (SYR) 09:15 Miami (MIA)
AA 4780 Non-stop Embraer EMB 175 (E75) 3:29 Effective 2025-11-08 through 2025-12-13
Sat 05:46 Syracuse (SYR) 09:15 Miami (MIA)
AA 4780 Non-stop Embraer EMB 175 (E75) 3:29 Effective from 2026-01-10
Mon-Fri,Sun 14:38 Chicago O'Hare (ORD) 3 16:20 Minneapolis/Saint Paul (MSP) 1
AA 4780 Non-stop Embraer EMB 175 (E75) 1:42 Effective 2025-06-05 through 2025-07-03
Daily 15:20 Chicago O'Hare (ORD) 3 16:59 Minneapolis/Saint Paul (MSP) 1
AA 4780 Non-stop Embraer EMB 175 (E75) 1:39 Effective 2025-08-06 through 2025-09-02
Mon-Fri,Sun 16:50 Minneapolis/Saint Paul (MSP) 1 18:51 Chicago O'Hare (ORD) 3
AA 4780 Non-stop Embraer EMB 175 (E75) 2:01 Effective 2025-06-05 through 2025-07-03
Fri 17:00 Chicago O'Hare (ORD) 3 18:39 Minneapolis/Saint Paul (MSP) 1
AA 4780 Non-stop Embraer EMB 175 (E75) 1:39 Operates only on 2025-07-04
Daily 17:36 Charlottesville (CHO) 19:00 New York LaGuardia (LGA) B
AA 4780 Non-stop Embraer EMB 175 (E75) 1:24 Effective 2025-10-06 through 2025-11-01
Daily 17:46 Minneapolis/Saint Paul (MSP) 1 19:35 Chicago O'Hare (ORD) 3
AA 4780 Non-stop Embraer EMB 175 (E75) 1:49 Effective 2025-08-06 through 2025-09-02
Daily 18:02 Charlottesville (CHO) 19:28 New York LaGuardia (LGA) B
AA 4780 Non-stop Embraer EMB 175 (E75) 1:26 Effective 2025-09-03 through 2025-10-05
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This flight number is listed as serving the following routes:


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American Airlines flight AA 4780: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
American Airlines AA4780
05:46
Syracuse (SYR)

09:15
Miami (MIA)
Effective 2025-11-08 through 2025-12-13
Mon
-
Tue
-
Wed
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Thu
-
Fri
-
Sat
Sun
-
Duration: 3:29, non-stop
Embraer EMB 175 (E75)
American Airlines AA4780
05:46
Syracuse (SYR)

09:15
Miami (MIA)
Effective from 2026-01-10
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 3:29, non-stop
Embraer EMB 175 (E75)
American Airlines AA4780
14:38
Chicago O'Hare (ORD) 3

16:20
Minneapolis/Saint Paul (MSP) 1
Effective 2025-06-05 through 2025-07-03
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:42, non-stop
Embraer EMB 175 (E75)
American Airlines AA4780
15:20
Chicago O'Hare (ORD) 3

16:59
Minneapolis/Saint Paul (MSP) 1
Effective 2025-08-06 through 2025-09-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:39, non-stop
Embraer EMB 175 (E75)
American Airlines AA4780
16:50
Minneapolis/Saint Paul (MSP) 1

18:51
Chicago O'Hare (ORD) 3
Effective 2025-06-05 through 2025-07-03
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 2:01, non-stop
Embraer EMB 175 (E75)
American Airlines AA4780
17:00
Chicago O'Hare (ORD) 3

18:39
Minneapolis/Saint Paul (MSP) 1
Operates only on 2025-07-04
Mon
-
Tue
-
Wed
-
Thu
-
Fri
Sat
-
Sun
-
Duration: 1:39, non-stop
Embraer EMB 175 (E75)
American Airlines AA4780
17:36
Charlottesville (CHO)

19:00
New York LaGuardia (LGA) B
Effective 2025-10-06 through 2025-11-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:24, non-stop
Embraer EMB 175 (E75)
American Airlines AA4780
17:46
Minneapolis/Saint Paul (MSP) 1

19:35
Chicago O'Hare (ORD) 3
Effective 2025-08-06 through 2025-09-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:49, non-stop
Embraer EMB 175 (E75)
American Airlines AA4780
18:02
Charlottesville (CHO)

19:28
New York LaGuardia (LGA) B
Effective 2025-09-03 through 2025-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:26, non-stop
Embraer EMB 175 (E75)
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This flight number is listed as serving the following routes:
  • Charlottesville (CHO) - New York LaGuardia (LGA)
  • Chicago O'Hare (ORD) - Minneapolis/Saint Paul (MSP)
  • Syracuse (SYR) - Miami (MIA)
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