American Airlines flight AA 4646: Multiple routes

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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
Mon-Fri,Sun 06:09 Raleigh/Durham (RDU) 2 07:29 Ronald Reagan Washington (DCA) 2
AA 4646 Non-stop Embraer EMB 175 (E75) 1:20 Effective 2025-06-05 through 2025-07-04
Sat 07:40 Raleigh/Durham (RDU) 2 09:00 Ronald Reagan Washington (DCA) 2
AA 4646 Non-stop Embraer EMB 175 (E75) 1:20 Effective 2025-06-07 through 2025-06-28
Daily 08:05 John Glenn Columbus (CMH) 09:29 Ronald Reagan Washington (DCA) 2
AA 4646 Non-stop Embraer EMB 175 (E75) 1:24 Effective 2025-08-06 through 2025-09-02
Daily 10:00 Ronald Reagan Washington (DCA) 2 13:11 Fort Myers (RSW)
AA 4646 Non-stop Embraer EMB 175 (E75) 3:11 Effective 2025-11-02 through 2025-12-02
Daily 10:00 Ronald Reagan Washington (DCA) 2 12:54 Fort Myers (RSW)
AA 4646 Non-stop Embraer EMB 175 (E75) 2:54 Effective 2025-12-03 through 2025-12-17
Daily 10:00 Ronald Reagan Washington (DCA) 2 12:58 Fort Myers (RSW)
AA 4646 Non-stop Embraer EMB 175 (E75) 2:58 Effective 2025-12-18 through 2026-01-05
Daily 13:24 Fort Myers (RSW) 15:59 Ronald Reagan Washington (DCA) 2
AA 4646 Non-stop Embraer EMB 175 (E75) 2:35 Effective 2025-12-03 through 2025-12-17
Daily 13:57 Fort Myers (RSW) 16:29 Ronald Reagan Washington (DCA) 2
AA 4646 Non-stop Embraer EMB 175 (E75) 2:32 Effective 2025-11-02 through 2025-12-02
Daily 14:02 Fort Myers (RSW) 16:29 Ronald Reagan Washington (DCA) 2
AA 4646 Non-stop Embraer EMB 175 (E75) 2:27 Effective 2025-12-18 through 2026-01-05
Mon-Fri,Sun 15:55 New York LaGuardia (LGA) B 17:11 Boston Logan (BOS) B
AA 4646 Non-stop Embraer EMB 175 (E75) 1:16 Effective 2025-05-05 through 2025-06-04
Mon-Fri,Sun 16:00 New York LaGuardia (LGA) B 17:20 Boston Logan (BOS) B
AA 4646 Non-stop Embraer EMB 175 (E75) 1:20 Valid until 2025-05-04
Mon-Fri,Sun 17:50 Boston Logan (BOS) B 19:08 New York LaGuardia (LGA) B
AA 4646 Non-stop Embraer EMB 175 (E75) 1:18 Valid until 2025-05-04
Mon-Fri,Sun 18:00 Boston Logan (BOS) B 19:23 New York LaGuardia (LGA) B
AA 4646 Non-stop Embraer EMB 175 (E75) 1:23 Effective 2025-05-05 through 2025-06-04
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This flight number is listed as serving the following routes:


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American Airlines flight AA 4646: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
American Airlines AA4646
06:09
Raleigh/Durham (RDU) 2

07:29
Ronald Reagan Washington (DCA) 2
Effective 2025-06-05 through 2025-07-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:20, non-stop
Embraer EMB 175 (E75)
American Airlines AA4646
07:40
Raleigh/Durham (RDU) 2

09:00
Ronald Reagan Washington (DCA) 2
Effective 2025-06-07 through 2025-06-28
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:20, non-stop
Embraer EMB 175 (E75)
American Airlines AA4646
08:05
John Glenn Columbus (CMH)

09:29
Ronald Reagan Washington (DCA) 2
Effective 2025-08-06 through 2025-09-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:24, non-stop
Embraer EMB 175 (E75)
American Airlines AA4646
10:00
Ronald Reagan Washington (DCA) 2

13:11
Fort Myers (RSW)
Effective 2025-11-02 through 2025-12-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 3:11, non-stop
Embraer EMB 175 (E75)
American Airlines AA4646
10:00
Ronald Reagan Washington (DCA) 2

12:54
Fort Myers (RSW)
Effective 2025-12-03 through 2025-12-17
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:54, non-stop
Embraer EMB 175 (E75)
American Airlines AA4646
10:00
Ronald Reagan Washington (DCA) 2

12:58
Fort Myers (RSW)
Effective 2025-12-18 through 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:58, non-stop
Embraer EMB 175 (E75)
American Airlines AA4646
13:24
Fort Myers (RSW)

15:59
Ronald Reagan Washington (DCA) 2
Effective 2025-12-03 through 2025-12-17
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:35, non-stop
Embraer EMB 175 (E75)
American Airlines AA4646
13:57
Fort Myers (RSW)

16:29
Ronald Reagan Washington (DCA) 2
Effective 2025-11-02 through 2025-12-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:32, non-stop
Embraer EMB 175 (E75)
American Airlines AA4646
14:02
Fort Myers (RSW)

16:29
Ronald Reagan Washington (DCA) 2
Effective 2025-12-18 through 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:27, non-stop
Embraer EMB 175 (E75)
American Airlines AA4646
15:55
New York LaGuardia (LGA) B

17:11
Boston Logan (BOS) B
Effective 2025-05-05 through 2025-06-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:16, non-stop
Embraer EMB 175 (E75)
American Airlines AA4646
16:00
New York LaGuardia (LGA) B

17:20
Boston Logan (BOS) B
Valid until 2025-05-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:20, non-stop
Embraer EMB 175 (E75)
American Airlines AA4646
17:50
Boston Logan (BOS) B

19:08
New York LaGuardia (LGA) B
Valid until 2025-05-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:18, non-stop
Embraer EMB 175 (E75)
American Airlines AA4646
18:00
Boston Logan (BOS) B

19:23
New York LaGuardia (LGA) B
Effective 2025-05-05 through 2025-06-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:23, non-stop
Embraer EMB 175 (E75)
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This flight number is listed as serving the following routes:
  • Boston Logan (BOS) - New York LaGuardia (LGA)
  • John Glenn Columbus (CMH) - Ronald Reagan Washington (DCA)
  • Raleigh/Durham (RDU) - Ronald Reagan Washington (DCA)
  • Ronald Reagan Washington (DCA) - Fort Myers (RSW)
All American Airlines flights
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