American Airlines flight AA 4443: Multiple routes

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FLIGHT SCHEDULE
Direct Flights:
Daily 08:06 New York LaGuardia (LGA) B 10:23 Cincinnati (CVG)
AA 4443 Non-stop Embraer EMB 175 (E75) 2:17 Effective 2025-09-03 through 2025-10-05
Daily 08:10 New York LaGuardia (LGA) B 10:23 Cincinnati (CVG)
AA 4443 Non-stop Embraer EMB 175 (E75) 2:13 Valid until 2025-05-09
Mon-Fri 08:10 New York LaGuardia (LGA) B 10:23 Cincinnati (CVG)
AA 4443 Non-stop Embraer EMB 175 (E75) 2:13 Effective 2025-05-12 through 2025-06-04
Daily 08:20 Philadelphia (PHL) 10:29 Indianapolis (IND)
AA 4443 Non-stop Embraer EMB 175 (E75) 2:09 Effective 2025-08-06 through 2025-09-02
Mon-Fri 10:35 Chicago O'Hare (ORD) 3 13:56 Charleston (CHS)
AA 4443 Non-stop Embraer EMB 175 (E75) 2:21 Effective 2025-06-05 through 2025-06-30
Wed-Fri 10:35 Chicago O'Hare (ORD) 3 13:56 Charleston (CHS)
AA 4443 Non-stop Embraer EMB 175 (E75) 2:21 Effective 2025-07-02 through 2025-07-04
Daily 11:04 Indianapolis (IND) 12:55 Philadelphia (PHL)
AA 4443 Non-stop Embraer EMB 175 (E75) 1:51 Effective 2025-08-06 through 2025-09-02
Mon-Fri 14:26 Charleston (CHS) 16:03 Chicago O'Hare (ORD) 3
AA 4443 Non-stop Embraer EMB 175 (E75) 2:37 Effective 2025-06-05 through 2025-06-30
Wed,Thu 14:26 Charleston (CHS) 16:03 Chicago O'Hare (ORD) 3
AA 4443 Non-stop Embraer EMB 175 (E75) 2:37 Effective 2025-07-02 through 2025-07-03
Fri 14:28 Charleston (CHS) 16:05 Chicago O'Hare (ORD) 3
AA 4443 Non-stop Embraer EMB 175 (E75) 2:37 Operates only on 2025-07-04
Daily 14:49 Key West (EYW) 17:55 Philadelphia (PHL)
AA 4443 Non-stop Embraer EMB 175 (E75) 3:06 Effective 2025-10-26 through 2025-11-01
Daily 14:50 Key West (EYW) 17:55 Philadelphia (PHL)
AA 4443 Non-stop Embraer EMB 175 (E75) 3:05 Effective 2025-12-03 through 2026-01-05
Daily 14:51 Key West (EYW) 17:55 Philadelphia (PHL)
AA 4443 Non-stop Embraer EMB 175 (E75) 3:04 Effective from 2026-02-12
Daily 14:54 Key West (EYW) 17:55 Philadelphia (PHL)
AA 4443 Non-stop Embraer EMB 175 (E75) 3:01 Effective 2025-11-02 through 2025-12-02
Daily 14:59 Key West (EYW) 17:55 Philadelphia (PHL)
AA 4443 Non-stop Embraer EMB 175 (E75) 2:56 Effective 2026-01-06 through 2026-02-11
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This flight number is listed as serving the following routes:


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American Airlines flight AA 4443: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
American Airlines AA4443
08:06
New York LaGuardia (LGA) B

10:23
Cincinnati (CVG)
Effective 2025-09-03 through 2025-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:17, non-stop
Embraer EMB 175 (E75)
American Airlines AA4443
08:10
New York LaGuardia (LGA) B

10:23
Cincinnati (CVG)
Valid until 2025-05-09
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:13, non-stop
Embraer EMB 175 (E75)
American Airlines AA4443
08:10
New York LaGuardia (LGA) B

10:23
Cincinnati (CVG)
Effective 2025-05-12 through 2025-06-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
-
Duration: 2:13, non-stop
Embraer EMB 175 (E75)
American Airlines AA4443
08:20
Philadelphia (PHL)

10:29
Indianapolis (IND)
Effective 2025-08-06 through 2025-09-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:09, non-stop
Embraer EMB 175 (E75)
American Airlines AA4443
10:35
Chicago O'Hare (ORD) 3

13:56
Charleston (CHS)
Effective 2025-06-05 through 2025-06-30
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
-
Duration: 2:21, non-stop
Embraer EMB 175 (E75)
American Airlines AA4443
10:35
Chicago O'Hare (ORD) 3

13:56
Charleston (CHS)
Effective 2025-07-02 through 2025-07-04
Mon
-
Tue
-
Wed
Thu
Fri
Sat
-
Sun
-
Duration: 2:21, non-stop
Embraer EMB 175 (E75)
American Airlines AA4443
11:04
Indianapolis (IND)

12:55
Philadelphia (PHL)
Effective 2025-08-06 through 2025-09-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:51, non-stop
Embraer EMB 175 (E75)
American Airlines AA4443
14:26
Charleston (CHS)

16:03
Chicago O'Hare (ORD) 3
Effective 2025-06-05 through 2025-06-30
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
-
Duration: 2:37, non-stop
Embraer EMB 175 (E75)
American Airlines AA4443
14:26
Charleston (CHS)

16:03
Chicago O'Hare (ORD) 3
Effective 2025-07-02 through 2025-07-03
Mon
-
Tue
-
Wed
Thu
Fri
-
Sat
-
Sun
-
Duration: 2:37, non-stop
Embraer EMB 175 (E75)
American Airlines AA4443
14:28
Charleston (CHS)

16:05
Chicago O'Hare (ORD) 3
Operates only on 2025-07-04
Mon
-
Tue
-
Wed
-
Thu
-
Fri
Sat
-
Sun
-
Duration: 2:37, non-stop
Embraer EMB 175 (E75)
American Airlines AA4443
14:49
Key West (EYW)

17:55
Philadelphia (PHL)
Effective 2025-10-26 through 2025-11-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 3:06, non-stop
Embraer EMB 175 (E75)
American Airlines AA4443
14:50
Key West (EYW)

17:55
Philadelphia (PHL)
Effective 2025-12-03 through 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 3:05, non-stop
Embraer EMB 175 (E75)
American Airlines AA4443
14:51
Key West (EYW)

17:55
Philadelphia (PHL)
Effective from 2026-02-12
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 3:04, non-stop
Embraer EMB 175 (E75)
American Airlines AA4443
14:54
Key West (EYW)

17:55
Philadelphia (PHL)
Effective 2025-11-02 through 2025-12-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 3:01, non-stop
Embraer EMB 175 (E75)
American Airlines AA4443
14:59
Key West (EYW)

17:55
Philadelphia (PHL)
Effective 2026-01-06 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:56, non-stop
Embraer EMB 175 (E75)
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This flight number is listed as serving the following routes:
  • Charleston (CHS) - Chicago O'Hare (ORD)
  • Indianapolis (IND) - Philadelphia (PHL)
  • Key West (EYW) - Philadelphia (PHL)
  • New York LaGuardia (LGA) - Cincinnati (CVG)
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